Royal Air Force Typhoon FGR4s have operated alongside French warplanes in a combined operation on an hidden munitions depot in Syria employed by the IS group, as stated by the UK's MoD.
The site, pinpointed through intelligence, was believed to be storing arms and explosives, the statement said, and was located in mountainous terrain just above the historic site of Palmyra in central Syria.
"Our fighter planes used Paveway IV guided bombs to target a series of approach shafts providing entry to the facility... initial indications indicate the objective was successfully hit," officials stated.
There was no indication of any civilian casualties in the operation on Saturday evening and each participating jet returned safely, the defence officials confirmed.
The British jets were supported by a Voyager refuelling tanker.
The Islamic State group - referred to as ISIS - established jihadist rule over significant areas in Syria and Iraq prior to its 2019 collapse.
"This operation shows our UK leadership, and resolve to work closely with our allies, to eradicate any revival of IS and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey stated.
UK warplanes have performed surveillance missions over Syria to "deter any attempted comeback" of IS after its defeat at the climactic battle in Baghuz in 2019, the MoD reported.
"I extend gratitude to the personnel of British forces involved in this mission for their expertise and their courage," Healey added. "Including them were thousands of British personnel on duty over the festive period. This operation, to eliminate militants who endanger our way of life, demonstrates how our armed forces are prepared to act, all year round, ensuring Britain's security within its borders and influential overseas."
During December, the United States armed forces conducted what it described as a "major assault" on IS targets in Syria, after an ambush claimed the lives of two American soldiers and a civilian linguist in Palmyra.
The United Nations reports IS still has between 5,000 and 7,000 combatants in Syria and Iraq.
